Home » Disruption of Protein-Protein Interfaces: In Search of New Inhibitors by Stefano Mangani
Disruption of Protein-Protein Interfaces: In Search of New Inhibitors Stefano Mangani

Disruption of Protein-Protein Interfaces: In Search of New Inhibitors

Stefano Mangani

Published July 9th 2013
ISBN : 9783642379987
Hardcover
161 pages
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 About the Book 

Disruption of Protein-Protein Interfaces reviews the latest developments and future perspectives in drug discovery at protein-protein interfaces. The authors detail experimental and computational tools to tackle the subject and highlight theMoreDisruption of Protein-Protein Interfaces reviews the latest developments and future perspectives in drug discovery at protein-protein interfaces. The authors detail experimental and computational tools to tackle the subject and highlight the contribution of the Italian research community to the field. Evidence shows that blocking or modulating protein-protein interactions might lead to the development of useful new drugs. Consequently, in recent years great effort has been dedicated to unveiling the molecular details of protein-protein interfaces by structural techniques e.g. X-ray diffraction, NMR spectroscopy. This book, written and edited by leaders in the field, provides examples from the literature of successes and failures to develop drug-like molecules effective in interacting at protein-protein interfaces.